Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors

<p>Abstract</p> <p>Background</p> <p>TRPA1 has been implicated in both chemo- and mechanosensation. Recent work demonstrates that inhibiting TRPA1 function reduces mechanical hypersensitivity produced by inflammation. Furthermore, a broad range of chemical irritants req...

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Bibliographic Details
Main Authors: Moran Magdalene M, del Camino Donato, Kerstein Patrick C, Stucky Cheryl L
Format: Article
Language:English
Published: SAGE Publishing 2009-04-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/19