Utilizing the genomically adjusted radiation dose (GARD) to personalize adjuvant radiotherapy in triple negative breast cancer managementResearch in context

Background: Utilizing the linear quadratic model and the radiosensitivity index (RSI), we have derived an expression for the genomically adjusted radiation dose (GARD) to model radiation dose effect. We hypothesize GARD is associated with local recurrence and can be used to optimize individual tripl...

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Bibliographic Details
Main Authors: Kamran A. Ahmed, Casey L. Liveringhouse, Matthew N. Mills, Nicholas B. Figura, G. Daniel Grass, Iman R. Washington, Eleanor E. Harris, Brian J. Czerniecki, Peter W. Blumencranz, Steven A. Eschrich, Jacob G. Scott, Roberto Diaz, Javier F. Torres-Roca
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419305377