Control of HCV Replication With iMIRs, a Novel Anti-RNAi Agent

Control of HCV Replication With iMIRs, a Novel Anti-RNAi Agent

MicroRNAs (miRNAs) serve important roles in regulating various physiological activities through RNA interference (RNAi). miR-122 is an important mediator of RNAi that is known to control hepatitis C virus (HCV) replication and is being investigated in clinical trials as a target for anti-HCV therapy...

Full description

Bibliographic Details
Main Authors: Saori Itami, Yutaka Eguchi, Takayuki Mizutani, Eriko Aoki, Tadaaki Ohgi, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Hiroshi I Suzuki, Norifumi Kawada, Yoshiki Murakami
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
anti-sense oligonucleotide
hepatitis C virus
interferon
locked nucleic acid
miRNA
RNA interference
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300038

Internet

http://www.sciencedirect.com/science/article/pii/S2162253116300038

Similar Items