Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy

Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy

Abstract Post-hepatectomy liver dysfunction is a life-threatening morbidity that lacks efficient therapy. Bioactive lipids involved in macrophage polarization crucially regulate tissue injury and regeneration. Herein, we investigate the key bioactive lipids that mediate the cytotherapeutic potential...

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Bibliographic Details
Main Authors: Hang Sun, Shibo Sun, Gang Chen, Haorong Xie, Sheng Yu, Xinxin Lin, Jianping Qian, Cungui Mao, Hongxian Peng, Hao Chen, Xuefang Chen, Yiyi Li, Cuiting Liu, Junmin Shi, Bili Zhu, Linghong Guo, Qingping Li, Pengxiang Huang, Yiran Wei, Xixin Huang, Meiqi Liu, Zhonglin Cui, Qifan Zhang, Jie Zhou, Chuanjiang Li, Kai Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03616-9

Internet

https://doi.org/10.1038/s41419-021-03616-9

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