Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties

<p>Abstract</p> <p>Over-expressed in numerous cancers, Ubiquitin-like containing PHD Ring Finger 1 (UHRF1, also known as ICBP90 or Np95<it>) </it>is characterized by a SRA domain (Set and Ring Associated) which is found only in the UHRF family. UHRF1 constitutes a compl...

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Bibliographic Details
Main Authors: Schini-Kerth Valérie B, Fuhrmann Guy, Etienne-Selloum Nelly, Mousli Marc, Sharif Tanveer, Alhosin Mahmoud, Bronner Christian
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/41