Ca2+ Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca2+-Dependent Nuclear Gene Expression

In polarized cells or cells with complex geometry, clustering of plasma-membrane (PM) ion channels is an effective mechanism for eliciting spatially restricted signals. However, channel clustering is also seen in cells with relatively simple topology, suggesting it fulfills a more fundamental role i...

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Bibliographic Details
Main Authors: Krishna Samanta, Pulak Kar, Gary R. Mirams, Anant B. Parekh
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715006166