Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients.

BACKGROUND: The CYP2E1 and GSTM1 genes encode metabolic enzymes that have key functions in drug modification and elimination. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the possible effects of CYP2E1 and GSTM1 polymorphisms in 71 leprosy patients and in 110 individuals from the general populati...

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Bibliographic Details
Main Authors: Pablo Pinto, Claudio Guedes Salgado, Ney Santos, Dayse O Alencar, Sidney Santos, Mara H Hutz, Ândrea Ribeiro-dos-Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471857?pdf=render