Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

The isolation and propagation of oligodendroglial cells from postnatal animals can be impractical for functional genetic studies. This study highlights the potential of a new approach to rapidly generate oligodendrocytes and their progenitors from mouse embryonic and induced pluripotent stem cells,...

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Bibliographic Details
Main Authors: Angela M. Lager, Olivia G. Corradin, Jared M. Cregg, Matthew S. Elitt, H. Elizabeth Shick, Benjamin L. L. Clayton, Kevin C. Allan, Hannah E. Olsen, Mayur Madhavan, Paul J. Tesar
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06102-7