Two Distinct Categories of Focal Deletions in Cancer Genomes.

Two Distinct Categories of Focal Deletions in Cancer Genomes.

One of the key questions about genomic alterations in cancer is whether they are functional in the sense of contributing to the selective advantage of tumor cells. The frequency with which an alteration occurs might reflect its ability to increase cancer cell growth, or alternatively, enhanced insta...

Full description

Bibliographic Details
Main Authors: Megha Rajaram, Jianping Zhang, Tim Wang, Jinyu Li, Cem Kuscu, Huan Qi, Mamoru Kato, Vladimir Grubor, Robert J Weil, Aslaug Helland, Anne-Lise Borrenson-Dale, Kathleen R Cho, Douglas A Levine, Alan N Houghton, Jedd D Wolchok, Lois Myeroff, Sanford D Markowitz, Scott W Lowe, Michael Zhang, Alex Krasnitz, Robert Lucito, David Mu, R Scott Powers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689739?pdf=render

Internet

http://europepmc.org/articles/PMC3689739?pdf=render

Similar Items