The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery

The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery

BackgroundInflammasome-mediated activation of caspase-1 regulates inflammatory responses and pyroptosis. We analyzed possible associations between inflammasome-related genes and immune reconstitution in HIV-infected antiretroviral therapy (ART)-treated patients.MethodsCross-sectional, case–control s...

Full description

Bibliographic Details
Main Authors: Alessandra Bandera, Michela Masetti, Massimiliano Fabbiani, Mara Biasin, Antonio Muscatello, Nicola Squillace, Mario Clerici, Andrea Gori, Daria Trabattoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
inflammasome
caspase
pyroptosis
HIV
immune reconstitution
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00214/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00214/full

Similar Items