Targeting oncogenic Notch signaling with SERCA inhibitors

Abstract P-type ATPase inhibitors are among the most successful and widely prescribed therapeutics in modern pharmacology. Clinical transition has been safely achieved for H+/K+ ATPase inhibitors such as omeprazole and Na+/K+-ATPase inhibitors like digoxin. However, this is more challenging for Ca2+...

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Bibliographic Details
Main Authors: Luca Pagliaro, Matteo Marchesini, Giovanni Roti
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-020-01015-9