CRP/anti-CRP antibodies assembly on the surfaces of cell remnants switches their phagocytic clearance towards inflammation

CRP/anti-CRP antibodies assembly on the surfaces of cell remnants switches their phagocytic clearance towards inflammation

Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease characteris¬ed by the production of autoantibodies, formation of immune complexes (IC), and activation of complement that ultimately fuel acute and/or chronic inflammation. Accumulation in blood and tissues of post-apoptot...

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Bibliographic Details
Main Authors: Christina eJanko, Sandra eFranz, Luis E. Munoz, Stefan eSiebig, Silke eWinkler, Georg eSchett, Kirsten eLauber, Ahmed eSheriff, Johan eVan Der Vlag, Martin eHerrmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Immunology
Subjects:
Inflammation
immune complexes
SLE
anti-CRP
anti-dsDNA
Clearance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00070/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00070/full

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