Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity.

Hepatitis C virus (HCV) genomes and proteins are present in human brain tissues although the impact of HIV/HCV co-infection on neuropathogenesis remains unclear. Herein, we investigate HCV infectivity and effects on neuronal survival and neuroinflammation in conjunction with HIV infection.Human micr...

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Bibliographic Details
Main Authors: Pornpun Vivithanaporn, Ferdinand Maingat, Liang-Tzung Lin, Hong Na, Christopher D Richardson, Babita Agrawal, Eric A Cohen, Jack H Jhamandas, Christopher Power
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2943470?pdf=render