Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila

Loss of mitochondrial function often leads to neurodegeneration and is thought to be one of the underlying causes of neurodegenerative diseases such as Parkinson's disease (PD). However, the precise events linking mitochondrial dysfunction to neuronal death remain elusive. PTEN-induced putative...

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Bibliographic Details
Main Authors: Aditya Sen, Sreehari Kalvakuri, Rolf Bodmer, Rachel T. Cox
Format: Article
Language:English
Published: The Company of Biologists 2015-06-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/8/6/577