Neuropeptide Y is produced by adipose tissue macrophages and regulates obesity-induced inflammation.

Neuropeptide Y (NPY) is induced in peripheral tissues such as adipose tissue with obesity. The mechanism and function of NPY induction in fat are unclear. Given the evidence that NPY can modulate inflammation, we examined the hypothesis that NPY regulates the function of adipose tissue macrophages (...

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Bibliographic Details
Main Authors: Kanakadurga Singer, David L Morris, Kelsie E Oatmen, Tianyi Wang, Jennifer DelProposto, Taleen Mergian, Kae Won Cho, Carey N Lumeng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3589443?pdf=render