Interleukin-12 and Peripheral Blood Invariant Natural Killer T Cells as an Axis in Childhood Asthma Pathogenesis

Interleukin-12 and Peripheral Blood Invariant Natural Killer T Cells as an Axis in Childhood Asthma Pathogenesis

Interleukin-12 (IL-12) is a key cytokine involved in regulating the balance between TH1 and TH2 cells by promoting TH1 response. A reduced capacity to produce this cytokine could lead to aberrant TH2 development. On the same aspect significant impact of IL-12 on invariant natural killer T (iNKT) cel...

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Bibliographic Details
Main Authors: Magdy M Zedan, Farha A El-Chennawi, Ashraf E Fouda
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2010-03-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Asthmatic children
Clinical asthma severity
invariant Natural killer T (iNKT) cells
IL-12
Peripheral blood
Pulmonary function tests
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/268

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/268

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