Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription

The role of human papillomavirus 16 (HPV16) in human cancers is well established; however, to date there are no antiviral therapeutics that are available for combatting these cancers. To identify such targets, we must enhance the understanding of the viral life cycle. Innate immune genes (IIGs) are...

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Bibliographic Details
Main Authors: Claire D. James, Christian T. Fontan, Raymonde Otoa, Dipon Das, Apurva T. Prabhakar, Xu Wang, Molly L. Bristol, Iain M. Morgan
Format: Article
Language:English
Published: American Society for Microbiology 2020-01-01
Series:mSphere
Subjects:
e6
e7
Online Access:https://doi.org/10.1128/mSphere.00828-19