Apoptosis in the liver of male <em>db/db</em> mice during the development of obesity and type 2 diabetes

Apoptosis in the liver of male <em>db/db</em> mice during the development of obesity and type 2 diabetes

Obesity and diabetes mellitus are known to lead to the development of metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). The mechanisms of programmed cell death are actively involved in maintaining cellular homeostasis along development of NAFLD. Proteins of the BCL-2 family are key r...

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Bibliographic Details
Main Authors: S. V. Michurina, I. Yu. Ishchenko, S. A. Arkhipov, M. A. Cherepanova, D. V. Vasendin, E. L. Zavjalov
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2020-07-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
db/db mice
obesity
type 2 diabetes mellitus (dm2)
liver
endothelial cells
hepatocytes
bcl-2
bad
Online Access:https://vavilov.elpub.ru/jour/article/view/2510

Internet

https://vavilov.elpub.ru/jour/article/view/2510

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