Recent Discoveries in the Androgen Receptor Pathway in Castration-Resistant Prostate Cancer

Recent Discoveries in the Androgen Receptor Pathway in Castration-Resistant Prostate Cancer

The androgen receptor (AR) is the main therapeutic target in advanced prostate cancer, because it regulates the growth and progression of prostate cancer cells. Patients may undergo multiple lines of AR-directed treatments, including androgen-deprivation therapy, AR signaling inhibitors (abiraterone...

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Bibliographic Details
Main Authors: Daisuke Obinata, Mitchell G. Lawrence, Kenichi Takayama, Nicholas Choo, Gail P. Risbridger, Satoru Takahashi, Satoshi Inoue
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
androgen receptor
castration-resistant prostate cancer
transcription factors
octamer transcription factor 1
preclinical models
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.581515/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.581515/full

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