Correcting for Naturally Occurring Mass Isotopologue Abundances in Stable-Isotope Tracing Experiments with PolyMID

Stable-isotope tracing is a method to measure intracellular metabolic pathway utilization by feeding a cellular system a stable-isotope-labeled tracer nutrient. The power of the method to resolve differential pathway utilization is derived from the enrichment of metabolites in heavy isotopes that ar...

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Bibliographic Details
Main Authors: Heesoo Jeong, Yan Yu, Henrik J. Johansson, Frank C. Schroeder, Janne Lehtiö, Nathaniel M. Vacanti
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/5/310