High-dose methotrexate is effective for prevention of isolated CNS relapse in diffuse large B cell lymphoma

High-dose methotrexate is effective for prevention of isolated CNS relapse in diffuse large B cell lymphoma

Abstract The role of central nervous system (CNS) prophylaxis with high-dose methotrexate (HDMTX) in DLBCL is controversial. In this retrospective study, we evaluated the efficacy of prophylactic HDMTX on isolated CNS relapse, concomitant CNS and systemic relapse, systemic relapse, and survival outc...

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Bibliographic Details
Main Authors: Shin Yeu Ong, Sanjay de Mel, Nicholas Francis Grigoropoulos, Yunxin Chen, Yan Chin Tan, Melinda Si Yun Tan, Lawrence Cheng Kiat Ng, Yuh Shan Lee, Colin Phipps, Yeow Tee Goh, Kar Ying Yong, Xin Liu, Wee Joo Chng, Soon Thye Lim, Chandramouli Nagarajan
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-021-00535-y

Internet

https://doi.org/10.1038/s41408-021-00535-y

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