Secondary structure changes in ApoA-I Milano (R173C) are not accompanied by a decrease in protein stability or solubility.

Secondary structure changes in ApoA-I Milano (R173C) are not accompanied by a decrease in protein stability or solubility.

Apolipoprotein A-I (apoA-I) is the main protein of high-density lipoprotein (HDL) and a principal mediator of the reverse cholesterol transfer pathway. Variants of apoA-I have been shown to be associated with hereditary amyloidosis. We previously characterized the G26R and L178H variants that both p...

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Bibliographic Details
Main Authors: Jitka Petrlova, Jonathan Dalla-Riva, Matthias Mörgelin, Maria Lindahl, Ewa Krupinska, Karin G Stenkula, John C Voss, Jens O Lagerstedt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3995965?pdf=render

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http://europepmc.org/articles/PMC3995965?pdf=render

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