How driving endonuclease genes can be used to combat pests and disease vectors

How driving endonuclease genes can be used to combat pests and disease vectors

Abstract Driving endonuclease genes (DEGs) spread through a population by a non-Mendelian mechanism. In a heterozygote, the protein encoded by a DEG causes a double-strand break in the homologous chromosome opposite to where its gene is inserted and when the break is repaired using the homologue as...

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Bibliographic Details
Main Authors: H. Charles J. Godfray, Ace North, Austin Burt
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Biology
Subjects:
Gene drive
Gene editing
Endonucleases
CRISPR-Cas9
Vector control
Pest control
Online Access:http://link.springer.com/article/10.1186/s12915-017-0420-4

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http://link.springer.com/article/10.1186/s12915-017-0420-4

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