An Optimized Competitive-Aging Method Reveals Gene-Drug Interactions Underlying the Chronological Lifespan of Saccharomyces cerevisiae

An Optimized Competitive-Aging Method Reveals Gene-Drug Interactions Underlying the Chronological Lifespan of Saccharomyces cerevisiae

The chronological lifespan of budding yeast is a model of aging and age-related diseases. This paradigm has recently allowed genome-wide screening of genetic factors underlying post-mitotic viability in a simple unicellular system, which underscores its potential to provide a comprehensive view of t...

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Bibliographic Details
Main Authors: J. Abraham Avelar-Rivas, Michelle Munguía-Figueroa, Alejandro Juárez-Reyes, Erika Garay, Sergio E. Campos, Noam Shoresh, Alexander DeLuna
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Genetics
Subjects:
post-mitotic aging
genetic analysis
high-throughput screening
gene-drug interactions
Saccharomyces cerevisiae
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00468/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00468/full

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