MicroRNA-495 confers inhibitory effects on cancer stem cells in oral squamous cell carcinoma through the HOXC6-mediated TGF-β signaling pathway

MicroRNA-495 confers inhibitory effects on cancer stem cells in oral squamous cell carcinoma through the HOXC6-mediated TGF-β signaling pathway

Abstract Background Oral squamous cell carcinoma (OSCC) is associated with high morbidity and ranks sixth among malignancies worldwide. Increasing evidence suggests that microRNAs (miRNAs or miRs) play a critical role in regulating cancer stem cells (CSCs), which drive the proliferation and spread o...

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Bibliographic Details
Main Authors: Xiaolong You, Zhengyu Zhou, Wen Chen, Xiaoyong Wei, Heqiang Zhou, Wenzheng Luo
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
microRNA-495
Oral squamous cell carcinoma
Cancer stem cells
Homeobox C6
TGF-β signaling pathway
Migration
Online Access:http://link.springer.com/article/10.1186/s13287-020-1576-3

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http://link.springer.com/article/10.1186/s13287-020-1576-3

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