Ablation of Aquaporin-9 Ameliorates the Systemic Inflammatory Response of LPS-Induced Endotoxic Shock in Mouse

Septic shock is the most severe complication of sepsis, being characterized by a systemic inflammatory response following bacterial infection, leading to multiple organ failure and dramatically high mortality. Aquaporin-9 (AQP9), a membrane channel protein mainly expressed in hepatocytes and leukocy...

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Bibliographic Details
Main Authors: Angela Tesse, Patrizia Gena, Michael Rützler, Giuseppe Calamita
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
LPS
Online Access:https://www.mdpi.com/2073-4409/10/2/435