E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320a.

BACKGROUND AND OBJECTIVE: Transcriptional factor E2A is crucial for the normal development and differentiation of B and T lymphocytes. Dysregulation of E2A leads to leukemia and tumorigenesis of some solid tumors. The expression and clinical significance of E2A as well as its role in colorectal canc...

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Bibliographic Details
Main Authors: Ao Huang, Hongchao Zhao, Yingjun Quan, Runsen Jin, Bo Feng, Minhua Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3890311?pdf=render