ALDH-1-positive cells exhibited a radioresistant phenotype that was enhanced with hypoxia in cervical cancer

Abstract Background We have previously found there was a small subpopulation of cells with cancer stem cell-like phenotype ALDH-1 in cervical cancer. Radiotherapy has been applied in most of the cervical cancer. However,the mechanisms underlying radioresistance still remained elusive. Our study is t...

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Bibliographic Details
Main Authors: Tingting Yao, Xueling Weng, Yao Yao, Chunxian Huang, Jing Li, Yongpai Peng, Rongchun Lin, Zhongqiu Lin
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-020-07337-8