Conflicting Roles of 20-HETE in Hypertension and Stroke

Conflicting Roles of 20-HETE in Hypertension and Stroke

Hypertension is the most common modifiable risk factor for stroke, and understanding the underlying mechanisms of hypertension and hypertension-related stroke is crucial. 20-hydroxy-5, 8, 11, 14-eicosatetraenoic acid (20-HETE), which plays an important role in vasoconstriction, autoregulation, endot...

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Bibliographic Details
Main Authors: Shashank Shekhar, Kevin Varghese, Man Li, Letao Fan, George W. Booz, Richard J. Roman, Fan Fan
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
cytochrome P450
hypertension
stroke
cerebral autoregulation
endothelial dysfunction
vascular remodeling
vascular inflammation
blood-brain barrier
angiogenesis
Online Access:https://www.mdpi.com/1422-0067/20/18/4500

Internet

https://www.mdpi.com/1422-0067/20/18/4500

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