Tertiary Lymphoid Structures in Cancer: The Double-Edged Sword Role in Antitumor Immunity and Potential Therapeutic Induction Strategies

Tertiary Lymphoid Structures in Cancer: The Double-Edged Sword Role in Antitumor Immunity and Potential Therapeutic Induction Strategies

The complex tumor microenvironment (TME) plays a vital role in cancer development and dramatically determines the efficacy of immunotherapy. Tertiary lymphoid structures (TLSs) within the TME are well recognized and consist of T cell-rich areas containing dendritic cells (DCs) and B cell-rich areas...

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Bibliographic Details
Main Authors: Wendi Kang, Zhichao Feng, Jianwei Luo, Zhenhu He, Jun Liu, Jianzhen Wu, Pengfei Rong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
tertiary lymphoid structures
tumor immunity
lymphoid neogenesis
bioengineering
immunotherapy
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.689270/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.689270/full

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