The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo

The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo

A biodegradable poly(lactic-co-glycolic acid) loading atorvastatin calcium (AC) nanoparticles (AC-PLGA-NPs) were prepared by probe ultrasonication and evaporation method aiming at improving the oral bioavailability of AC. The effects of experimental parameters, including stabilizer species, stabiliz...

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Bibliographic Details
Main Authors: Zhenbao Li, Wenhui Tao, Dong Zhang, Chunnuan Wu, Binbin Song, Shang Wang, Tianyang Wang, Mingming Hu, Xiaohong Liu, Yongjun Wang, Yinghua Sun, Jin Sun
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Atorvastatin calcium
AC-PLGA-NPs
Probe ultrasonication and evaporation method
Oral bioavailability
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616300770

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http://www.sciencedirect.com/science/article/pii/S1818087616300770

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