Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro

Increased β-synuclein (Sncb) expression has been described in the aging visual system. Sncb functions as the physiological antagonist of α-synuclein (Snca), which is involved in the development of neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases. However, the exact function o...

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Bibliographic Details
Main Authors: Katrin Brockhaus, Michael R. R. Böhm, Harutyun Melkonyan, Solon Thanos
Format: Article
Language:English
Published: SAGE Publishing 2018-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718755706