Dynamic simulation and metabolome analysis of long-term erythrocyte storage in adenine-guanosine solution.

Although intraerythrocytic ATP and 2,3-bisphophoglycerate (2,3-BPG) are known as direct indicators of the viability of preserved red blood cells and the efficiency of post-transfusion oxygen delivery, no current blood storage method in practical use has succeeded in maintaining both these metabolite...

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Bibliographic Details
Main Authors: Taiko Nishino, Ayako Yachie-Kinoshita, Akiyoshi Hirayama, Tomoyoshi Soga, Makoto Suematsu, Masaru Tomita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796775?pdf=render