Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair.

Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair.

BACKGROUND: The therapeutic efficiency of bone marrow mononuclear cells (BMMNCs) autologous transplantation for myocardial infarction (MI) remains low. Here we developed a novel strategy to improve cardiac repair by preconditioning BMMNCs via angiotensin II type 2 receptor (AT2R) stimulation. METHOD...

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Bibliographic Details
Main Authors: Yinchuan Xu, Xinyang Hu, Lihan Wang, Zhi Jiang, Xianbao Liu, Hong Yu, Zhaocai Zhang, Huiqiang Chen, Han Chen, Gustav Steinhoff, Jun Li, Jian'an Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3858344?pdf=render

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http://europepmc.org/articles/PMC3858344?pdf=render

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