The Chromatin Response to Double-Strand DNA Breaks and Their Repair

Cellular DNA is constantly being damaged by numerous internal and external mutagenic factors. Probably the most severe type of insults DNA could suffer are the double-strand DNA breaks (DSBs). They sever both DNA strands and compromise genomic stability, causing deleterious chromosomal aberrations t...

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Bibliographic Details
Main Authors: Radoslav Aleksandrov, Rossitsa Hristova, Stoyno Stoynov, Anastas Gospodinov
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/8/1853