Modulation of iron metabolism in aging and in Alzheimer’s disease: relevance of the choroid plexus.

Modulation of iron metabolism in aging and in Alzheimer’s disease: relevance of the choroid plexus.

Iron is essential for mammalian cellular homeostasis. However, in excess, it promotes free radical formation and is associated with aging-related progressive deterioration and with neurodegenerative disorders such as Alzheimer’s disease (AD). There are no mechanisms to excrete iron, which makes iron...

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Bibliographic Details
Main Authors: Sandro Da Mesquita, Ana Catarina Ferreira, Joao C Sousa, Nadine Correia Santos, Margarida eCorreia-Neves, Nuno eSousa, Joana A Palha, Fernanda eMarques
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Aging
Cerebrospinal Fluid
Choroid Plexus
Iron
Alzheimer’s disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00025/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00025/full

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