Enhanced stability and polyadenylation of select mRNAs support rapid thermogenesis in the brown fat of a hibernator

During hibernation, animals cycle between torpor and arousal. These cycles involve dramatic but poorly understood mechanisms of dynamic physiological regulation at the level of gene expression. Each cycle, Brown Adipose Tissue (BAT) drives periodic arousal from torpor by generating essential heat. W...

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Bibliographic Details
Main Authors: Katharine R Grabek, Cecilia Diniz Behn, Gregory S Barsh, Jay R Hesselberth, Sandra L Martin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04517