Cefepime and Amoxicillin Increase Metabolism and Enhance Caspofungin Tolerance of Candida albicans Biofilms

Cefepime and Amoxicillin Increase Metabolism and Enhance Caspofungin Tolerance of Candida albicans Biofilms

It is well known that prolonged antibiotic therapy alters the mucosal microbiota composition, increasing the risk of invasive fungal infection (IFI) in immunocompromised patients. The present study investigated the direct effect of β-lactam antibiotics cefepime (CEF) and amoxicillin (AMOX) on biofil...

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Bibliographic Details
Main Authors: Rossana de Aguiar Cordeiro, Antonio Jose de Jesus Evangelista, Rosana Serpa, Ana Raquel Colares de Andrade, Patrícia Bruna Leite Mendes, Jonathas Sales de Oliveira, Lucas Pereira de Alencar, Vandbergue Santos Pereira, Reginaldo Gonçalves Lima-Neto, Raimunda Nogueira Brilhante, José Júlio Costa Sidrim, Débora Castelo Brancode Souza Collares Maia, Marcos Fábio Gadelha Rocha
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Microbiology
Subjects:
β-lactam antibiotics
cefepime
amoxicillin
Candida albicans
biofilm
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01337/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01337/full

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