Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

Both the subjective response to d-amphetamine and the risk for amphetamine addiction are known to be heritable traits. Because subjective responses to drugs may predict drug addiction, identifying alleles that influence acute response may also provide insight into the genetic risk factors for drug a...

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Bibliographic Details
Main Authors: Amy B Hart, Barbara E Engelhardt, Margaret C Wardle, Greta Sokoloff, Matthew Stephens, Harriet de Wit, Abraham A Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429486?pdf=render