MFG-E8 released by apoptotic endothelial cells triggers anti-inflammatory macrophage reprogramming.

Apoptotic endothelial cells are an important component of the "response to injury" process. Several atherosclerosis risk factors such as hyperglycemia and oxidized low-density lipoproteins, and immune injuries, such as antibodies and complement, induce endothelial cell apoptosis. While end...

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Bibliographic Details
Main Authors: Marie-Joëlle Brissette, Stéphanie Lepage, Anne-Sophie Lamonde, Isabelle Sirois, Jessika Groleau, Louis-Philippe Laurin, Jean-François Cailhier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3340380?pdf=render