Identification of Suppressors of top-2 Embryonic Lethality in Caenorhabditis elegans

Identification of Suppressors of top-2 Embryonic Lethality in Caenorhabditis elegans

Topoisomerase II is an enzyme with important roles in chromosome biology. This enzyme relieves supercoiling and DNA and RNA entanglements generated during mitosis. Recent studies have demonstrated that Topoisomerase II is also involved in the segregation of homologous chromosomes during the first me...

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Bibliographic Details
Main Authors: Nirajan Bhandari, Christine Rourke, Thomas Wilmoth, Alekya Bheemreddy, David Schulman, Dina Collins, Harold E. Smith, Andy Golden, Aimee Jaramillo-Lambert
Format: Article
Language:English
Published: Oxford University Press 2020-04-01
Series:G3: Genes, Genomes, Genetics
Subjects:
top-2
c. elegans
meiosis
topoisomerase ii
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400927

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400927

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