Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients

Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients

Lung cancer is the leading cause of cancer-related mortality worldwide. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapies, based on the evaluation of EGFR mutations, have shown dramatic clinical benefits. EGFR mutation assays are mainly performed on tumor biopsies, wh...

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Bibliographic Details
Main Authors: Haiyan E. Liu, Meghah Vuppalapaty, Charles Wilkerson, Corinne Renier, Michael Chiu, Clementine Lemaire, James Che, Melissa Matsumoto, James Carroll, Steve Crouse, Violet R. Hanft, Stefanie S. Jeffrey, Dino Di Carlo, Edward B. Garon, Jonathan Goldman, Elodie Sollier
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
Vortex technology
circulating tumor cell
total liquid biopsy
epidermal grow factor receptor
EGFR mutation analysis
Non-small cell carcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.572895/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.572895/full

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