Can follicular helper T cells be targeted to improve vaccine efficacy? [version 1; referees: 3 approved]

The success of most vaccines relies on the generation of antibodies to provide protection against subsequent infection; this in turn depends on a robust germinal centre (GC) response that culminates in the production of long-lived antibody-secreting plasma cells. The size and quality of the GC respo...

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Bibliographic Details
Main Authors: Michelle A. Linterman, Danika L. Hill
Format: Article
Language:English
Published: F1000 Research Ltd 2016-01-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-88/v1