Can follicular helper T cells be targeted to improve vaccine efficacy? [version 1; referees: 3 approved]
The success of most vaccines relies on the generation of antibodies to provide protection against subsequent infection; this in turn depends on a robust germinal centre (GC) response that culminates in the production of long-lived antibody-secreting plasma cells. The size and quality of the GC respo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2016-01-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/5-88/v1 |