Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains

<p>Abstract</p> <p>Background</p> <p>The Nef protein of Human Immunodeficiency Viruses optimizes viral spread in the infected host by manipulating cellular transport and signal transduction machineries. Nef also boosts the infectivity of HIV particles by an unknown mech...

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Main Authors: Geyer Matthias, Breuer Sebastian, Glass Bärbel, Leibrecht Iris, Rauch Susanne, Munte Claudia E, Tibroni Nadine, Krautkrämer Ellen, Brügger Britta, Kräusslich Hans-Georg, Kalbitzer Hans, Wieland Felix T, Fackler Oliver T
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/70