Caspase-1-like regulation of the proPO-system and role of ppA and caspase-1-like cleaved peptides from proPO in innate immunity.

Caspase-1-like regulation of the proPO-system and role of ppA and caspase-1-like cleaved peptides from proPO in innate immunity.

Invertebrates rely on innate immunity to respond to the entry of foreign microorganisms. One of the important innate immune responses in arthropods is the activation of prophenoloxidase (proPO) by a proteolytic cascade finalized by the proPO-activating enzyme (ppA), which leads to melanization and t...

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Bibliographic Details
Main Authors: Miti Jearaphunt, Chadanat Noonin, Pikul Jiravanichpaisal, Seiko Nakamura, Anchalee Tassanakajon, Irene Söderhäll, Kenneth Söderhäll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24722332/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24722332/?tool=EBI

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