Case Report: Therapeutic Response to Chemo-Immunotherapy in an Advanced Large Cell Lung Carcinoma Patient With Low Values of Multiple Predictive Biomarkers

Case Report: Therapeutic Response to Chemo-Immunotherapy in an Advanced Large Cell Lung Carcinoma Patient With Low Values of Multiple Predictive Biomarkers

Immune checkpoint inhibitors have revolutionized the treatments of lung cancers, and multiple predictive biomarkers alone or in combination help clinicians with the appropriate therapeutic selections. Recently, chemo-immunotherapy has been recommended for treating advanced non-small cell lung cancer...

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Bibliographic Details
Main Authors: Guihua Wang, Qin Chai, Yajie Xiao, Wenying Peng, Miao Teng, Jingyi Wang, Hanqing Lin, Xiaofan Su, Lin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
large cell lung carcinoma
PD-L1 expression
tumor mutational burden
CD8(+) tumor-infiltrating lymphocytes
chemo-immunotherapy
predictive biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607416/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.607416/full

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