Mitochondrial Homeostasis and Signaling in Parkinson’s Disease

The loss of dopaminergic (DA) neurons in the substantia nigra leads to a progressive, long-term decline of movement and other non-motor deficits. The symptoms of Parkinson’s disease (PD) often appear later in the course of the disease, when most of the functional dopaminergic neurons have been lost....

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Bibliographic Details
Main Authors: Antonella Scorziello, Domenica Borzacchiello, Maria Jose Sisalli, Rossana Di Martino, Micaela Morelli, Antonio Feliciello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
PKA
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00100/full