Functional expression of a penicillin acylase from the extreme thermophile <it>Thermus thermophilus</it> HB27 in <it>Escherichia coli</it>

Functional expression of a penicillin acylase from the extreme thermophile <it>Thermus thermophilus</it> HB27 in <it>Escherichia coli</it>

<p>Abstract</p> <p>Background</p> <p>Penicillin acylases (PACs) are enzymes of industrial relevance in the manufacture of β-lactam antibiotics. Development of a PAC with a longer half-life under the reaction conditions used is essential for the improvement of the operat...

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Bibliographic Details
Main Authors: Torres Leticia L, Ferreras Eloy R, Cantero Ángel, Hidalgo Aurelio, Berenguer José
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Microbial Cell Factories
Subjects:
Penicillin acylase
<it>Thermus thermophilus</it>
Pre-pro-protein
Autoprocessing
Thermophile
Thermozyme
Online Access:http://www.microbialcellfactories.com/content/11/1/105

Internet

http://www.microbialcellfactories.com/content/11/1/105

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