Preclinical PET Neuroimaging of [C]Bexarotene

Activation of retinoid X receptors (RXRs) has been proposed as a therapeutic mechanism for the treatment of neurodegeneration, including Alzheimer's and Parkinson's diseases. We previously reported radiolabeling of a Food and Drug Administration-approved RXR agonist, bexarotene, by copper-...

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Bibliographic Details
Main Authors: Benjamin H. Rotstein PhD, Michael S. Placzek PhD, Hema S. Krishnan PhD, Aleksandra Pekošak MPharm, Thomas Lee Collier PhD, Changning Wang PhD, Steven H. Liang PhD, Ethan S. Burstein PhD, Jacob M. Hooker PhD, Neil Vasdev PhD
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2016-08-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1177/1536012116663054