ANOVA-HD: Analysis of variance when both input and output layers are high-dimensional.

Modern genomic data sets often involve multiple data-layers (e.g., DNA-sequence, gene expression), each of which itself can be high-dimensional. The biological processes underlying these data-layers can lead to intricate multivariate association patterns. We propose and evaluate two methods to deter...

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Bibliographic Details
Main Authors: Gustavo de Los Campos, Torsten Pook, Agustin Gonzalez-Reymundez, Henner Simianer, George Mias, Ana I Vazquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243251